Zika Virus Trafficking and Interactions in the Human Male Reproductive Tract
نویسندگان
چکیده
منابع مشابه
P-17: Expression of Cell Surface Toll-Like Receptors in the Human Male Reproductive Tract
Background: Male infertility refers to the inability of a male to achieve a pregnancy in a fertile female. The root of many causes of infertility is miscommunication between immune and reproductive system. Male reproductive system is very sensitive and vulnerable, infections can hinder maturation and movement of spermatozoa lead to impaired fertility.All species need an immediate reply to the m...
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Clusterin is a 75-80 kDa heterodimenc glycoprotein that was first identified as a component of the fluid from the ram rete testes (Fritz et al, 1983). Over the past 15 years, the protein has been purified, or its cognate mRNA cloned, from a number of different species and diverse tissues, including several tissues of the reproductive tract (see Table 1). The role, or, more probably, roles, of t...
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Zika virus (ZIKV) is a mosquito-transmitted virus that can cause severe defects in an infected fetus. ZIKV is also transmitted by sexual contact, although the relative importance of sexual transmission is unclear. To better understand the role of sexual transmission in ZIKV pathogenesis, a nonhuman primate (NHP) model of vaginal transmission was developed. ZIKV was readily transmitted to mature...
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The production of anti-Zika virus (ZIKV) therapeutics has become increasingly important as the propagation of the devastating virus continues largely unchecked. Notably, a causal relationship between ZIKV infection and neurodevelopmental abnormalities has been widely reported, yet a specific mechanism underlying impaired neurological development has not been identified. Here, we report on the d...
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Infertility is an uncommon manifestation of genitourinary tract tuberculosis. Anatomic obstruction by granulomas or distortion of the normal anatomy by fibrosis surrounding the reproductive tract structures is the commonest cause of infertility. The diagnosis is usually based on a suggestive history along with evidence of granulomatous infection on a tissue sample. The management depends on the...
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ژورنال
عنوان ژورنال: Pathogens
سال: 2018
ISSN: 2076-0817
DOI: 10.3390/pathogens7020051